Over the past two decades, there has been a re-emergence of interest in the interfaces between religion and spirituality and medicine and psychiatry. Religion and spirituality, as key elements of culture, influence normal development, attitudes, and behaviors pertaining to medical and psychiatric care, relationships with other individuals inside and outside the family, and the general worldview of a child, adolescent, and his or her family. Religion and spirituality are clinically valid, important, and helpful areas for clinicians to address in their assessment and clinical work with children, adolescents, and their families. This CCB seeks to raise awareness and foster discussion of the clinical issues involved. Attendees acquire an increased appreciation for and comfort level with religion and spirituality, and learn techniques for addressing these issues in their practices.