There is increasing consensus among clinicians, health care administrators, mental health care policy makers, and regulators that seclusion and restraint carry adverse consequences; and there is now a consistent attempt by some state mental health authorities and psychiatric facilities across the United States to decrease the use of restraint and seclusion. This SIG presents basic approaches to creating a restraint prevention initiative and provides a forum to explore recent best practices preventing the use of restraint and seclusion. Participants have a venue to discuss challenges and successful strategies to prevent the use of restraint and seclusion in clinical settings, including inpatient, residential treatment, schools, and juvenile justice settings.