Jill Ehrenreich-May, PhD

University of Miami
5665 Ponce de Leon Blvd
Room 315
Coral Gables, FL
USA 33146

25 The Unified Protocol for the Treatment of Emotional Disorders in Adolescence: A Transdiagnostic Approach to Anxiety and Depression

Additional applicant information: A. Personal Statement. I have expertise in the development, adaptation and evaluation of cognitive-behavioral treatment (CBT) protocols for youth, with particular interest in transdiagnostic models that respond to the broader spectrums and high co-occurrence of emotional disorder symptoms. Over five years as a Research Assistant Professor and Associate Director of the Child and Adolescent Fear and Anxiety Treatment Program in the Center for Anxiety and Related Disorders at Boston University from 2003-2008, I received extensive training in the development of cognitive-behavioral treatment protocols, their evaluation and implementation under the mentorship of Dr. David Barlow and colleagues. I recently completed a career development award (K23; MH073946) to evaluate a transdiagnostic CBT intervention approach for adolescents with any primary anxiety or depressive disorder (the Unified Protocol for the Treatment of Emotional Disorders in Adolescence [UP-A]; Ehrenreich-May et al., 2009) which emerged from these formative experiences. This main effects from this investigation are presently being summarized for publication. Additional evidence of my current expertise in treatment development and evaluation includes co-authorship of treatment manuals for adolescent panic disorder (Pincus, Ehrenreich & Mattis, 2008), and the adult Unified Protocol (Barlow et al., 2010), in addition to the UP-A manual and a concomitant Unified program for school-aged children, the Unified Protocol for Children: Emotion Detectives (UP-C; Ehrenreich-May & Bilek, 2009). A randomized, controlled trial of the UP-C, comparing its effects to a group CBT program targeting youth anxiety disorders is now underway at the University of Miami (UM). Since launching the Child and Adolescent Mood and Anxiety Treatment (CAMAT) Program at UM in Fall 2008, where I am an Associate Professor in the Departments of Psychology and Psychiatry, my expertise has expanded to include the independent recruitment, assessment, supervision and retention of children with internalizing disorders and their families in clinical research. This research clinic setting has become a highly-sought local resource for the treatment of anxiety and depressive disorders in South Florida, screening over 400 families and enrolling over 150 in on-going clinical research trials. During this time, I have been a PI on a recently completed three-site collaborative R34 from NICHD (HD65284) to develop and evaluate the feasibility of a CBT protocol for younger adolescents with autism and anxiety disorders. B. Positions and Honors Positions 2002-2003 Assistant Professor, Clinical Psychology Program, Department of Psychology, University of Central Florida 2003-2008 Assistant (Research) Professor, Clinical Psychology Program, Department of Psychology, Boston University 2003-2008 Associate Director, Child and Adolescent Fear and Anxiety Treatment Program in the Center for Anxiety and Related Disorders at Boston University 2008-2011 Assistant Professor, Department of Psychology, University of Miami 2008-Present Director, Child and Adolescent Mood and Anxiety Treatment Program at the University of Miami 2011-Present Associate Professor, Department of Psychology, University of Miami (awarded with Tenure) Honors 2004 Career Development Travel Award, Anxiety Disorders Association of America 2004-2008 Pediatric Research Loan Repayment Award, National Institutes of Health 2005-2011 Editorial Board, Journal of Anxiety Disorders 2006-2007 Associate Editor, The Behavior Therapist 2007-2009 Leader, Child and Adolescent Anxiety Disorders Special Interest Group, Association for Behavioral and Cognitive Therapies 2009-Present Editorial Board, Psychotherapy Theory, Research, Practice and Training 2011-Present Editorial Board, Journal of Clinical Child and Adolescent Psychology 2011-Present Associate Editor, Journal of Cognitive Psychotherapy C. Selected Publications (of 71 total publications) 1. Ehrenreich-May, J., & Chu, B.C. (in press). Transdiagnostic mechanisms and treatment of youth psychopathology. New York: Guilford Press. 2. Queen, A. H., & Ehrenreich-May, J. (in press). Anxiety-disordered adolescents with and without a comorbid depressive disorder: Variations in clinical presentation and emotion regulation. Journal of Emotional and Behavioral Disorders. 3. Santucci, L. C. & Ehrenreich-May, J. (in press). A randomized controlled trial of the Child Anxiety Multi-Day Program (CAMP) for separation anxiety disorder. Child Psychiatry and Human Development. 4. Bilek, E.L., & Ehrenreich-May, J. (2012). An open trial investigation of a transdiagnostic group treatment for children with anxiety and depressive symptoms. Behavior Therapy. Advance online publication. doi: 10.1016/j.beth.2012.04.007 5. Levin, L., Henderson, H.A., & Ehrenreich-May, J. (2012). Interpersonal predictors of early therapeutic alliance in a transdiagnostic cognitive behavioral intervention for adolescents with anxiety and depression. Psychotherapy, 49, 218-230. doi:10.1037/a00282265 6. Micco, J.A., Hirshfeld-Becker, D., Henin, A., & Ehrenreich-May, J. (2012). Content specificity of threat interpretation in anxious and non-clinical children. Cognitive Therapy and Research. Advance online publication. doi:10.1007/s10608-012-9438-7 7. Storch, E. A., Wood, J. J., Ehrenreich-May, J., Lewin, A. B., Jones, A. M., Park, J. M., & Murphy, T. K. (2012). Convergent and divergent validity and reliability of the Pediatric Anxiety Rating Scale. Journal of Autism and Developmental Disabilities. Advance online publication. doi:10.1007/s10803-012-1489-9 8. Allen, L. B., Tsao, J. C. I., Seidman, L., Ehrenreich-May, J., & Zeltzer, L. K. (2012). A unified, transdiagnostic treatment for adolescents with chronic pain and anxiety and depression. Cognitive and Behavioral Practice, 19, 56-67. doi:10.1016/j.cbpra.2011.04.007 9. Ehrenreich-May, J., & Bilek, E. L. (2012). The development of a transdiagnostic cognitive behavioral group intervention for childhood anxiety disorders and co-occurring depression symptoms. Cognitive and Behavioral Practice, 19(1), 41-55. doi:10.1016/j.cbpra.2011.02.003 10. Ehrenreich-May, J., Southam-Gerow, M. A., Hourigan, S. E., Wright, L. R., Pincus, D. B., & Weisz, J. R. (2011). Comparing characteristics of anxious and depressed youth in two different clinical contexts. Administration and Policy in Mental Health, 38(5), 398-411. 11. Barlow, D. H., Ellard, K. K., Fairholme, C. P., Farchione, T. J., Boisseau, C. L., Allen, L. B., & Ehrenreich-May, J. (2010). The unified protocol for transdiagnostic treatment of emotional disorders, therapist guide. New York: Oxford University Press. 12. Pincus, D. B., Ehrenreich-May, J., Whitton, S. W., Mattis, S. G., & Barlow, D. H. (2010). Cognitive-behavioral treatment of panic disorder in adolescence. Journal of Clinical Child and Adolescent Psychology, 39(5), 638-649. 13. Trosper, S. E., & Ehrenreich, J. T. (2010). The relationship between trait, expressive, and familial correlates of emotion regulation in a clinical sample of anxious youth. Journal of Emotional and Behavioral Disorders. 14. Ehrenreich, J. T., Goldstein, C. R., & Wright, L. R., & Barlow, D. H. (2009). Development of a unified protocol for the treatment of emotional disorders in youth. Child & Family Behavior Therapy, 31(1), 20-37. 15. Fairholme, C. P., Boisseau, C. L., Ellard, K. K., Ehrenreich, J. T., & Barlow, D. H. (2009). Emotions, emotion regulation and psychological treatment: A unified perspective. In A. Kring & D. Sloan (Eds.), Emotion regulation and psychopathology. New York: Guilford Press. 16. Landon-Bacow, T., Pincus, D. B., Ehrenreich, J. T., & Brody, L. (2009). The Metacognitions Questionnaire for Children: Development and validation in a clinical sample of children and adolescents with anxiety disorders. Journal of Anxiety Disorders, 23, 727-736. 17. Micco, J. A., & Ehrenreich, J. T. (2009). Validity and specificity of the Children’s Automatic Thoughts Scale in clinically anxious and non-clinical children. Cognitive Therapy and Research, 33(5), 532-536. 18. Santucci, L. C., Ehrenreich, J. T., Trosper, S., Bennett, S. M., & Pincus, D. B. (2009). Development and preliminary evaluation of a one-week summer treatment program for separation anxiety disorder. Cognitive and Behavioral Practice, 16, 317-331. 19. Trosper, S. E., Buzzella, B. A., Bennett, S. M., & Ehrenreich, J. T. (2009). Emotion regulation in youth with emotional disorders: Implications for a unified treatment approach. Clinical Child and Family Psychology Review, 12, 234-254. 20. Micco, J. A., & Ehrenreich, J. T. (2008). Children’s interpretation and avoidant response biases in response to non-salient and salient situations: Relationships with mothers’ threat perception and coping expectations. Journal of Anxiety Disorders, 22, 371-385. 21. Pincus, D. B., Ehrenreich, J. T., & Mattis, S. G. (2008). Mastery of anxiety and panic for adolescents: Therapist guide. New York: Oxford University Press. 22. Pincus, D. B., Santucci, L., Ehrenreich, J. T., & Eyberg, S. (2008). The implementation of modified parent- child interaction therapy for youth with separation anxiety disorder. Cognitive and Behavioral Practice, 15(2), 118-125. 23. Ehrenreich, J. T., Fairholme, C. P., Buzzella, B. A., Ellard, K. K., & Barlow, D. H. (2007). The role of emotion in psychological therapy. Clinical Psychology: Science and Practice, 14 (4), 422-428. 24. Ehrenreich, J. T., Buzzella, B. A., & Barlow, D. H. (2006). General principles for the treatment of emotional disorders across the lifespan. In S. Hofmann & J. Weinberger (Eds.) The art and science of psychotherapy. (pp. 191-209). New York: Brunner-Routledge. 25. Ehrenreich, J. T., & Gross, A. M. (2002). Biased attentional behavior in childhood anxiety: A review of theory and current empirical investigation. Clinical Psychology Review, 22(7), 991-1008. D. Research Support Current Support: R34 MH095959 La Greca (PI) 7/1/2012-6/30/2015 NIMH Coping with Adolescent Peer Victimization and Reducing Anxious/Depressed Symptoms This grant supports the development of a school-based, preventative intervention for adolescents that have experienced interpersonal peer victimization and have risk for future psychopathology, as evidenced by elevated self-reported anxiety or depression symptoms. Role: Co-Investigator Total Costs: $691,000 Provost Research Award Ehrenreich-May (PI) 7/1/2012-6/30/2013 University of Miami Cognitive-Behavioral Group Treatment for Childhood Anxiety and Depression Symptoms: A Randomized, Controlled Trial This research award aids in the support of an on-going randomized controlled trial comparing a transdiagnostic, cognitive behavioral treatment protocol (the Unified Protocol for Children: Emotion Detectives) to a “gold standard” CBT protocol for anxiety and depressive symptoms in children ages 7-12. Total Costs: $17,000 K99/R00 MH091183 Britton (PI) 10/01/2010 – 09/30/2015 Neuroimaging of Extinction Recall in Development and Adolescent Social Anxiety. NIMH The goal of this project is to characterize developmental and anxiety-related perturbations in the neural correlates of threat appraisal during extinction recall. Role: Co-Investigator Total Costs: $718,000 NARSAD Young Investigator Award Britton (PI) 07/2010 – 12/2012 Brain and Behavior Research Foundation Novel Treatment Strategy in Adolescent Anxiety: Implications for Depression The goal of this project is to investigate the effects of attention retraining in anxious adolescents undergoing cognitive behavioral therapy (CBT). The dot-probe attention task will measure changes in attention biases to threat and reward. The neural circuitry following active vs. placebo attention retraining will also be investigated. Role: Collaborator Total Costs: $60,000 Selected Completed Projects: R34 HD65284-01 Ehrenreich-May (PI) 10/01/09-9/30/11 NICHD 3/3 CBT for Anxiety Disorders in Autism: Adapting Treatment for Adolescents This three-site collaborative project developed and tested the feasibility of a cognitive behavioral treatment for younger adolescents with an anxiety disorder and high-functioning autism spectrum disorder. Following initial protocol development, the resultant treatment was evaluated for preliminary efficacy in a controlled trial. Total costs: $1,000,005 (across three sites) K23 MH073946-03 Ehrenreich (PI) 7/01/06-6/30/11 NIMH Treatment of Emotional Disorders in Adolescence The main goal of this project was to develop expertise in conducting clinical research to establish innovative and efficacious interventions for adolescents with emotional disorders. Total costs: $486,956 R44 MH079525-02 Dimeff (PI) 6/1/2008-5/30/10 NIMH Computer-based Training in Panic Control Treatment for Adolescents In this Phase 2 project, we developed an online training prototype for treatment providers working with adolescents diagnosed with panic disorder and evaluated it in a randomized, controlled trial comparing to alternate clinician training methods. Role: Co-Investigator/University of Miami Site PI Total costs: $921,542

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